Clinical Applications of Physics in Medicine (PHYS*7510)

Code and section: PHYS*7510*01

Term: Winter 2016

Instructor: Dennis Mücher


Course Information


Lecturer Office Email
Dennis Mücher MacN 224

Office hours

Thursday, 1 -3 pm in my office (MacN 224)
Please visit me at any time in my office or via email (


Day Time Location
Tuesday, Thursday 10:00 am – 11:30 am MacN 101

Lecture Content

Medical physics is a rapidly developing science field where the strong interference of physics, biology and medicine has a large and growing impact on our health care system. This course gives an overview about the physics foundations and recent technical developments of medical imaging and medical treatment techniques. A special emphasize is put on accelerator-based cancer therapy which revolutionizes the way cancer can be cured through special isotope production, hadron therapy and targeted radiation treatments. Topics include:


  • General image characteristics and image reconstruction
  • X-ray detection and X-ray radiography
  • Computed tomography
  • Planar scintigraphy, SPECT
  • PET and PET/CT
  • Ultrasound imaging
  • MRI


  • Afterloading
  • Cancer Treatment using photons and electrons
  • Foundations of hadron cancer therapy
  • Particle accelerators and nuclear reactions
  • Production of radioisotopes using ISOL
  • Targeted radiation cancer therapy

Course Materials


There is no single textbook which covers the complete course. I will be posting my lecture notes onto courselink. Anyway, for the first part (imaging) the two following books can be recommended:

  • • N. Smith, A. Webb: Introduction to Medical Imaging, Cambridge Univ. Press 2010: There is a hardcover (~100$) as well as an e-book version (~75$) available. Includes clinical examples and a good selection of exercises. This book will serve as a guideline for the first part of this lecture. Similar information can be found in
  • • M.A. Haidekker: Medical imaging technology, Springer 2013: Freely available online at the UofG library for all UofG Students (use PRIMO search). This book is slightly more technical and contains less clinical examples.
    The second part (treatment) partly covers recent developments and no single textbook is recommended. A good first overview is freely available at the NUPECC Homepage


Assessment Weight
Assignments 20%
Midterm (to be discussed in the first lecture) 30%
Final Exam (Thursday 21 April 2016, 7pm – 9pm) 50%

Graduate students are supposed to give an oral presentation on a selected topic, which counts as 10% of the assignments.

Course Policies

E-mail Communication

As per university regulations, all students are required to check their <> e-mail account regularly: e-mail is the official route of communication between the University and its students.

When You Cannot Meet a Course Requirement

When you find yourself unable to meet an in-course requirement because of illness or compassionate reasons, please advise the course instructor (or designated person, such as a teaching assistant) in writing, with your name, id#, and e-mail contact. See the undergraduate calendar for information on regulations and procedures for Academic Consideration.

Drop Date

The last date to drop one-semester courses, without academic penalty, is Friday, March 11, 2016. For regulations and procedures for Dropping Courses, see the Undergraduate Calendar.

Copies of out-of-class assignments

Keep paper and/or other reliable back-up copies of all out-of-class assignments: you may be asked to resubmit work at any time.


The University of Guelph is committed to creating a barrier-free environment. Providing services for students is a shared responsibility among students, faculty and administrators. This relationship is based on respect of individual rights, the dignity of the individual and the University community's shared commitment to an open and supportive learning environment. Students requiring service or accommodation, whether due to an identified, ongoing disability or a short-term disability should contact the Centre for Students with Disabilities as soon as possible.

For more information, contact CSD at 519-824-4120 ext. 56208 or email or see the accessibility website.

Academic Misconduct

The University of Guelph is committed to upholding the highest standards of academic integrity and it is the responsibility of all members of the University community – faculty, staff, and students – to be aware of what constitutes academic misconduct and to do as much as possible to prevent academic offences from occurring. University of Guelph students have the responsibility of abiding by the University's policy on academic misconduct regardless of their location of study; faculty, staff and students have the responsibility of supporting an environment that discourages misconduct. Students need to remain aware that instructors have access to and the right to use electronic and other means of detection.

Please note: Whether or not a student intended to commit academic misconduct is not relevant for a finding of guilt. Hurried or careless submission of assignments does not excuse students from responsibility for verifying the academic integrity of their work before submitting it. Students who are in any doubt as to whether an action on their part could be construed as an academic offence should consult with a faculty member or faculty advisor.

The Academic Misconduct Policy is detailed in the Undergraduate Calendar.

Recording of Materials

Presentations which are made in relation to course work—including lectures—cannot be recorded or copied without the permission of the presenter, whether the instructor, a classmate or guest lecturer. Material recorded with permission is restricted to use for that course unless further permission is granted.


The Academic Calendars are the source of information about the University of Guelph’s procedures, policies and regulations which apply to undergraduate, graduate and diploma programs.

Course Evaluation Information

The Department of Physics requires student assessment of all courses taught by the Department. These assessments provide essential feedback to faculty on their teaching by identifying both strengths and possible areas of improvement. In addition, annual student assessment of teaching provides part of the information used by the Department Tenure and Promotion Committee in evaluating the faculty member's contribution in the area of teaching.

The Department's teaching evaluation questionnaire invites student response both through numerically quantifiable data, and written student comments. In conformity with University of Guelph Faculty Policy, the Department Tenure and Promotions Committee only considers comments signed by students. Your instructor will see all signed and unsigned comments after final grades are submitted. Written student comments may also be used in support of a nomination for internal and external teaching awards.

NOTE: No information will be passed on to the instructor until after the final grades have been submitted.