Molecular Biophysics (PHYS*4540)
Code and section: PHYS*4540*01
Term: Winter 2022
Instructor: Vladimir Ladizhansky
|Vladimir Ladizhansky||SSC firstname.lastname@example.org|
Tuesday/Thursday, 11:30 am-12:50 pm
AD-S (Synchronous virtual) until January 24.
OOM LINK WILL BE DISTRIBUTED VIA COURSELINK AND EMAIL.
In-person component will be announced.
- Protein structure. Nucleic acids structure. Factors determining protein and nucleic acid structures. Protein Stability. Biomembranes. Membrane proteins and their functions. Membrane transport. Evolution and Protein Folding. Human perspective: conformational diseases.
- Review of biophysical methods for characterization of protein structure and dynamics. Nuclear Magnetic Resonance (NMR) and high-resolution structure determination in biomolecules.
- Various topics in structural biology and biophysics of proteins. (Students’ presentations)
- Applications of NMR to various problems in structural biophysics. (Students' presentations)
|Participation in discussions||5%|
Students will be asked to give two presentations
Students will have to write a research proposal based on one of their presentations.
- Lodish et al, “Molecular Cell Biology” 5th edition
- Charles R. Cantor and Paul R. Schimmel: “Biophysical chemistry” part I: The conformation of biological molecules.
- Additional literature (papers, lecture notes, links to online materials, etc.) will be distributed.
- Thomas E. Creighton, “Proteins: Structure and Molecular Properties”
- Karp, “Cell and Molecular Biology”
- Voet and Voet, “Biochemistry”
- Stryer, “Biochemistry”
- Alberts, "Molecular Biology of the Cell"
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- Undergraduate Calendar - Academic Consideration and Appeals
- Graduate Calendar - Grounds for Academic Consideration
- Associate Diploma Calendar - Academic Consideration, Appeals and Petitions
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- Undergraduate Calendar - Dropping Courses
- Graduate Calendar - Registration Changes
- Associate Diploma Calendar - Dropping Courses
Copies of Out-of-class Assignments
Keep paper and/or other reliable back-up copies of all out-of-class assignments: you may be asked to resubmit work at any time.
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- Undergraduate Calendar - Academic Misconduct
- Graduate Calendar - Academic Misconduct
Recording of Materials
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Please note that the ongoing COVID-19 pandemic may necessitate a revision of the format of course offerings and academic schedules. Any such changes will be announced via CourseLink and/or class email. All University-wide decisions will be posted on the COVID-19 website and circulated by email.